2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. LIM Kinase (LIMK)
  5. LIM Kinase (LIMK) Degrader

LIM Kinase (LIMK) Degrader

LIM Kinase (LIMK) Isoform Comparison

LIM Kinase (LIMK) Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-178122
    THNAN69
    		Degrader
    THNAN69 is a potent chemical probe degrader targeting LIMK2, with a DC50 value of 1 nM. THNAN69 can be used for the study of diseases driven by LIMK2 overexpression or dysregulation, such as cancers and ocular diseases.
  • HY-137346
    DD-03-156
    		Degrader 99.90%
    DD-03-156 is a potent and selective degrader of CDK17 and LIMK2. The selectivity and potency of DD-03-156 is exquisite and makes an advanced starting point for the development of a chemical probe for the degradation of CDK17 (Blue: VHL ligand (HY-112078), Black: linker HY-124380 (HY-124380)；Pink: BRAF inhibitor (HY-14660)).